If you’re relatively new to Photoshop, you might not know that it’s possible to highlight and/or remove the various options in dropdown menus. All you need to do is play around with the Edit->Menus screen to make your commonly used options more visible and to reduce clutter by hiding options that you’ve never touched in your life.
(via Orms Connect)

If you’ve ever tried saving a layered file in Photoshop CS5 that’s more than a 1GB in size, you’ve probably experienced pretty sluggish performance. This is because the program always does image compression on the file that shrinks the file size at the expense of your workflow. If you’re rich in hard drive space but short on time, Adobe has released a plugin called that lets you disable image compression, speeding up the saving of large layered files by 20x!
Save PSD, PSB images without compression (via Mac Performance Guide via Rob Galbraith)
Image credit: Speedometer by RevTimMedia